Fioricet® (Butalbital, Acetaminophen, and Caffeine Tablets USP) is supplied in tablet form for oral administration.
Each tablet contains the following active ingredients:
butalbital USP . . . . . . . . . . . .50 mg
acetaminophen USP . . . . . . 325 mg
caffeine USP . . . . . . . . . . . . .40 mg
Inactive Ingredients: crospovidone, FD&C Blue #1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid.
Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
Fioricet is used to treat tension headaches that are caused by muscle contractions.
Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Its use has been primarily associated with the pain relieving effects of acetaminophen (Tylenol) and the relaxation effects of butalbital. Caution in this regard is required because butalbital is habit-forming and potentially abusable.
What we can find the efficacy of fioricet here is the patient reviews: 85% headache surfers thought fioricet is very efficient for tension headache, migraine headache, and even neck pain. Some even think fioricet is a life saver and they can live and work as normal. Butalbital-containing analgesics may be effective as backup medications or when other medications are ineffective or cannot be used.
By Druglib, The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches. Despite their frequent clinical use for migraine, they have not been studied in placebo-controlled trials among patients with migraine.
Barbiturates can produce:
Butalbital-containing products (such as Fioricet) used for treating migraines can cause:
- Drug-induced headaches
- The need to detoxify
- Withdrawal symptoms
- Increased medical expenses
- Lower quality of life